Витамин В3 эффективен в борьбе с деменцией

Витамин В3 эффективен в борьбе с деменцией

Продолжая изыскания в целях эффективной борьбы с деменцией, специалисты из Национальных институтов здравоохранения США провели ряд экспериментов над мышами с заболеванием Альцгеймера. В результате было выявлено положительное влияние никотинамида рибозида (витамин В3) на когнитивные и физиологические функции животных. Ученые рассчитывают применить открытие в лечении деменции у людей, о чем заявили на страницах UPI.com.

Как известно, болезнь Альцгеймера вызывает нарушения процессов восстановления ДНК в тканях мозга, в результате чего возникают дисфункциональные расстройства митохондрий, нейронов, сопровождаемые воспалительными реакциями. Никотинамид рибозид позволяет нормализовать уровень никотинамидадениндинуклеотида – конфермента, важного для энергетического обмена и самообновления стволовых клеток. Кроме того, отмечено его участие в стрессоустойчивости и восстановлении ДНК.

В ход эксперимента с мышами, ученые установили положительную динамику у животных, получивших никотинамид рибозид. У них были менее повреждены ДНК, а также нервных клеток, наблюдалась повышенная нейропластичность, стволовые клетки образовывали большее количество нейронов. Гиппокамп, наиболее подверженный проявлениям деменции, под воздействием никотинамида рибозид восстанавливал ДНК, препятствуя дальнейшему ее повреждению.

Источник: medvesti.com
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